PF-3758309
Synonyms: 898044-15-0 (free base); 1279034-84-2 (HCl). |
CAS NO : 898044-15-0 |
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Molecular Formula: C25H30N8OS |
Molecular Weight: 490.62 |
Purity: 98% min |
Solubility: In DMSO |
Storage: -20°C |
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Remarks: PF-3758309 is an orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-3758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
Quality Control
Quality Control by H-NMR,C-NMR,LC-MS,HPLC. |
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