Alisertib
| Synonyms: MLN8237; MLN-8237; MLN 8237 |
| CAS NO : 1028486-01-2 |
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| Molecular Formula: C27H20ClFN4O4 |
| Molecular Weight: 518.9 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks:Alisertib, also known as MLN8237, is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
Quality Control
H-NMR,C-NMR,LC-MS,HPLC. |
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